After a simulation is ready, you can flip (in turning machines) or rotate (in milling machines) the workpiece. This is used when you are going to save the workpiece as a prefabricated workpiece. You can also flip or rotate in the middle of a simulation (pause the simulation) if your program is made to cut the workpiece from different directions.
Please note, that in turning programs, this can also be done automatically using the $InvertLathePart command, and in milling machines using the $RotateWorkpiece command.